Regulator of contact-mediated hemolysin

Details Regulator of contact-mediated hemolysin Regulator of contact-mediated hemolysin

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/04 (2006.01) C07K 14/245 (2006.01) C07K 14/35 (2006.01) C07K 16/12 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2163438

The present invention provides an isolated double-stranded nucleic acid and the protein encoded by such nucleic acid that regulates hemolysis. Additionally provided is a double-stranded nucleic acid positively regulated by the positive regulator of hemolysin. Finally, methods for detecting virulent M. tuberculosis infection and for immunizing against tuberculosis are provided.

L'invention concerne un acide nucléique isolé à double brin et la protéine codée par cet acide nucléique et qui règle l'hémolyse, ainsi qu'un acide nucléique à double brin positivement réglé par le régulateur positif de l'hémolysine. Finalement, l'invention concerne également des procédés de détection de l'infection virulente par M. tuberculosis et d'immunisation contre la tuberculose.

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