Methods and compositions for the specific coagulation of...

Details Methods and compositions for the specific coagulation of... Methods and compositions for the specific coagulation of...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/36 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/745 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2194369

Disclosed are various compositions and methods for use in achieving specific blood coagulation. This is exemplified by the specific in vivo coagulation of tumor vasculature, causing tumor regression, through the site-specific delivery of a coagulant using a bispecific antibody.

Cette invention se rapporte à diverses compositions et à divers procédés utilisés pour obtenir une coagulation du sang spécifique, telle que notamment la coagulation in vivo spécifique du système vasculaire de tumeurs, dans le but d'obtenir une régression de la tumeur, grâce à l'apport d'un coagulant, orienté sur des sites spécifiques, cet apport s'effectuant au moyen d'un anticorps bispécifique.

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