Stabilization of viral compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/14 (2006.01) A61K 39/29 (2006.01) A61K 47/00 (2006.01)

Patent

CA 2592323

This invention concerns stabilized virus compositions, preferably a herpes virus which may be an attenuated or genetically modified herpes simplex virus or varicella zoster virus, and a method of stabilizing viruses and immunizing preparations by the addition of sugars, preferably glucose and amino acids, preferably lysine.

La présente invention concerne des préparations virales stabilisées, de préférence un herpèsvirus pouvant être un virus herpès simplex atténué ou génétiquement modifié, ou un virus varicelle zoster atténué ou génétiquement modifié. La présente invention concerne également une méthode de stabilisation de virus et de préparations immunisantes par addition de sucres, préférentiellement le glucose, ainsi que d'acides aminés, préférentiellement la lysine.

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