Benzazole compounds for use in therapy

Details Benzazole compounds for use in therapy Benzazole compounds for use in therapy

C - Chemistry, Metallurgy

07

D

C07D 277/64 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/42 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) A61K 31/655 (2006.01) C07D 263/56 (2006.01) C07D 263/57 (2006.01) C07D 277/66 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2170508

There are disclosed herein benzazole compounds, exemplified by 2-(4-aminophenyl)benzothiazole and analogues or salts thereof, which exhibit very significant selective cytotoxic activity in respect of tumour cells, especially breast cancer cells, and which provide potentially useful chemotherapeutic agents for treatment of breast cancer.

L'invention concerne des composés de benzazole, à l'exemple du 2-(4-aminophényle)benzothiazole et de ses analogues ou sels, démontrant une activité cytotoxique sélective très remarquable à l'égard des cellules tumorales, notamment des cellules du cancer du poumon; ces composés constituent des agents chimiothérapeutiques potentiellement utiles pour le traitement du cancer du poumon.

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