A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2495487
The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of ZD6474 in combination with ionising radiation; and to the use of ZD6474 in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in a warm- blooded animal such as a human which is being treated with ionising radiation.
L'invention concerne un procédé de production d'un effet de réduction antiangiogénique et/ou de la perméabilité vasculaire chez un animal à sang chaud tel qu'un humain, en particulier une méthode de traitement du cancer, en particulier un cancer impliquant une tumeur solide, qui comprend l'administration de ZD6474 en combinaison avec le rayonnement ionisant. L'invention concerne également l'utilisation de ZD6474 dans la fabrication d'un médicament destiné à produire un effet de réduction antiangiogénique et/ou de la perméabilité vasculaire chez un animal à sang chaud tel qu'un humain qui est traité par rayonnement ionisant.
Astrazeneca Ab
Fetherstonhaugh & Co.
LandOfFree
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