Variant forms of urate oxidase and use thereof

Details Variant forms of urate oxidase and use thereof Variant forms of urate oxidase and use thereof

C - Chemistry, Metallurgy

12

N

C12N 9/06 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2604399

The present invention relates to genetically modified proteins with uricolytic activity. More specifically, the invention relates to proteins comprising truncated urate oxidases and methods for producing them, including PEGylated proteins comprising truncated urate oxidases.

L'invention concerne des protéines génétiquement modifiées possédant une activité uricolytique. L'invention porte plus spécifiquement sur des protéines comprenant des urate oxydases, dont des protéines PEGylées comprenant des urate oxydases tronquées, et sur leurs procédés de production.

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