Substituted quinolin-4-ylamine analogues

Details Substituted quinolin-4-ylamine analogues Substituted quinolin-4-ylamine analogues

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) C07D 401/04 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2531535

Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

L'invention concerne des analogues de quinoline-4-ylamine substituée. Ces composés sont des ligands que l'on peut utiliser pour moduler l'activité de récepteurs spécifiques in vivo ou in vitro, et qui sont particulièrement utiles dans le traitement d'états associés à l'activation pathologique de récepteurs chez l'homme, les animaux domestiques et le bétail. L'invention concerne des compositions pharmaceutiques et leurs procédés d'utilisation pour traiter de tels troubles, ainsi que des procédés d'utilisation de ces ligands dans des études de localisation de récepteurs.

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