Probes and methods for hepatitis c virus typing using...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/51 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) C40B 60/02 (2006.01) G01N 33/576 (2006.01)

Patent

CA 2549758

This invention provides compositions and methods for HCV typing, e.g., genotyping and/or subtyping. The compositions and methods of the invention can be used to assign an HCV isolate to one of at least five HCV types (for example, selected from types 1, 2, 3, 4, 5 or 6), or to one of at least five subtypes (for example, subtypes 1a/b/c, 2a/c, 2b, 3a, 4a, 5a or 6a). These methods integrate the hybridization data from a plurality of HCV typing probes in a multidimensional analysis to make an HCV type assignment for an HCV in an experimental sample. The invention also provides related compositions, including, for example, the HCV typing probes and HCV typing diagnostic kits.

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