Compositions comprising hiv protease inhibitor and...

Details Compositions comprising hiv protease inhibitor and... Compositions comprising hiv protease inhibitor and...

A - Human Necessities

61

K

A61K 31/426 (2006.01) A61K 31/00 (2006.01) A61K 31/40 (2006.01) A61K 31/496 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2555173

The present invention relates to methods for improving the pharmacokinetics of certain compounds useful as inhibitors of the HIV protease enzyme by inhibiting the enzyme activity of cytochrome P450. The present invention also relates to compositions comprising certain compounds useful as inhibitors of the HIV protease enzyme and at least one agent that inhibits the enzyme activity of cytochrome P450.

L'invention concerne des procédés d'amélioration des pharmacocinétiques de certains composés utiles en tant qu'inhibiteurs de l'enzyme de la protéase de VIH par inhibition de l'activité enzymatique du cytochrome P450. Cette invention porte aussi sur des compositions contenant certains composés utiles en tant qu'inhibiteurs de l'enzyme de la protéase de VIH et au moins un agent qui inhibe l'activité enzymatique du cytochrome P450.

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