Graft implant containing drug crystals

Details Graft implant containing drug crystals Graft implant containing drug crystals

A - Human Necessities

61

F

A61F 2/00 (2006.01) A61F 2/06 (2006.01)

Patent

CA 2620487

A method of incorporating drugs into an implantable medical device. In one variation, water insoluble drugs are used to form crystals within the porous structure of the device. Upon implantation, the drug crystals dissolve slowly and release the drug into the surrounding tissue. In one example, a water insoluble drug is crystallized within the pores of an ePTFE vascular graft.

On décrit un procédé d'incorporation de médicaments dans un dispositif médical implantable. Dans une variante, des médicaments insolubles dans l'eau sont utilisés pour former des cristaux à l'intérieur de la structure poreuse du dispositif. Après implantation, les cristaux de médicament se dissolvent lentement et libèrent le médicament dans le tissu environnant. Dans un exemple, un médicament insoluble dans l'eau est cristallisé à l'intérieur des pores d'un greffon vasculaire ePTFE.

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