C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 38/04 (2006.01) C07K 14/47 (2006.01)
Patent
CA 2628703
Anti-A.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies. The present invention relates to anti-A.beta. globulomer antibodies having a binding affinity to A.beta.(20-42) globulomer that is greater than the binding affinity of the antibody to A.beta.(1-42) globulomer, antigen-binding moieties thereof, hybridomas producing said antibodies, nucleic acids encoding said antibodies, vectors comprising said nucleic acids, host cells comprising said vectors, methods of producing said antibodies, compositions comprising said antibodies, therapeutic and diagnostic uses of said antibodies and corresponding methods relating to Alzheimer's disease and other amyloidoses.
L'invention concerne des anticorps anti-globulomère A.beta., des fractions de liaison aux antigènes de ceux-ci, des hybridomes , des acides nucléiques, des vecteurs, des cellules hôtescorrespondants, des procédés de production des anticorps, des compositions comprenant les anticorps, des utilisations de ceux-ci et des procédés d'utilisation des anticorps. L' invention concerne des anticorps anti-globulomère A.beta. possédant une affinité de liaison pour le globulomère A.beta.(20-42) supérieure à l'affinité de liaison de l'anticorps pour le globulomère A.beta.(1-42), des fractions de liaison aux antigènes de ceux-ci, des hybridomes produisant lesdits anticorps, des acides nucléiques codant les anticorps, des vecteurs comprenant lesdits acides nucléiques, des cellules hôtes comprenant lesdits vecteurs, des procédés de production des anticorps, des compositions comprenant lesdits anticorps, des utilisations thérapeutiques et diagnostiques des anticorps et des procédés correspondants relatifs à la maladie d'Alzheimer et d'autres amyloïdoses.
Barghorn Stefan
Ebert Ulrich
Hillen Heinz
Keller Patrick
Labkovsky Boris
Abbott Gmbh & Co. Kg.
Abbott Laboratories
Torys Llp
LandOfFree
Anti-a.beta. globulomer antibodies, antigen-binding moieties... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-a.beta. globulomer antibodies, antigen-binding moieties..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-a.beta. globulomer antibodies, antigen-binding moieties... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1451394