Use of a combination of morphine and at least one opiate...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/485 (2006.01) A61K 45/06 (2006.01) A61P 25/04 (2006.01) A61P 25/36 (2006.01)

Patent

CA 2637458

The present invention relates to the use of an inseparable combination of morphine and at least one opiate antagonist with a bioavailability of less than 5% on oral administration for producing a medicament to be administered orally for treatment of opiate dependency in humans and to the use of an inseparable combination of an opiate and at least one opiate antagonists with a bioavailability of less than 5% on oral administration for producing a medicament to be administered orally for prevention of non-oral opiate abuse in opiate addicts.

La présente invention concerne l~utilisation d~un mélange non séparable de morphine et d'au moins un antagoniste des opiacés ayant une biodisponibilité inférieure à 5 % par voie orale pour la fabrication d~un médicament pour administration orale pour le traitement de la dépendance aux opiacés chez les êtres humains, ainsi que l'utilisation d'un mélange non séparable d'un opiacé et d'au moins un antagonistes des opiacés avec une biodisponibilité inférieure à 5 % par voie orale pour la fabrication d~un médicament pour administration orale destiné à empêcher l'abus non oral d'opiacés chez les personnes dépendantes aux opiacés.

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