Ethanol solvate of...

C - Chemistry – Metallurgy – 07 – D

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C07D 405/04 (2006.01) A61K 31/453 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2397594

An ethanol solvate form of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4R-(3S--hydroxy-1- methyl)piperidinyl]-4H-1-benzopyran-4-one (Form II), a method of making Form II and a pharmaceutical composition comprising Form II for treating cancer.

L'invention concerne un solvate d'éthanol sous forme (-)-cis-2-(2-chlorophényl)-5,7-dihydroxy-8[4R-(3S-hydroxy-1-méthyl)pipéridinyl]-4H-1-benzopyran-4-one (forme II), ainsi qu'un procédé relatif à l'élaboration de la forme II en question et une composition renfermant ladite forme II.

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