C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/315 (2006.01) A61K 39/09 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2416224
The invention provides multiple antigenic peptides (MAPs) that confer protection against S. pneumoniae challenge. These multiple antigen peptides comprise peptides that immunospecifically bind to the monoclonal antibodies. Also provided are vaccines comprising such immunogenic peptides, and methods of conferring protective immunity against Streptococcus pneumoniae infection by administering a therapeutic composition comprising the MAPs of the invention.
La présente invention concerne des peptides à antigènes multiples (MAP) qui confèrent une protection contre l'infection par S. pneumoniae. Ces peptides à antigènes multiples comprennent des peptides qui se lient de manière immunospécifique aux anticorps monoclonaux. La présente invention concerne également des vaccins renfermant ces mêmes peptides immunogènes ainsi que des procédés qui permettent de conférer une immunité de protection contre l'infection par Streptococcus pneumoniae au moyen de l'administration d'une composition thérapeutique comprenant les MAP selon l'invention.
Ades Edwin W.
Carlone George M.
Johnson Scott E.
Jue Danny L.
Sampson Jacquelyn S.
Department Of Health And Human Services The Government Of The United States Of America As Represented By
Gowling Lafleur Henderson Llp
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