Genetic polymorphisms associated with stenosis, methods of...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2510895

The present invention is based on the discovery of genetic polymorphisms that are associated with stenosis. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.

L'invention concerne des polymorphismes génétiques associes à la sténose, et en particulier des molécules d'acides nucléiques contenant les polymorphismes, des protéines variantes codées par ces molécules, des réactifs pour la détection des molécules d'acides nucléiques polymorphiques et des protéines, et enfin des procédés relatifs à l'utilisation des acides nucléiques et des protéines ainsi que des procédés relatifs à l'utilisation de réactifs pour leur détection.

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