Pharmaceutical compositions having desirable bioavailability

Details Pharmaceutical compositions having desirable bioavailability Pharmaceutical compositions having desirable bioavailability

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 31/535 (2006.01) A61K 31/542 (2006.01) A61K 31/5575 (2006.01)

Patent

CA 2716994

The present invention is directed to the provision of pharmaceutical compositions. The compositions include a therapeutic agent and a relatively low amount of surfactant for providing higher bioavailability of the therapeutic agent. The compositions are particularly desirable as ophthalmic compositions in which the therapeutic agent is a prostaglandin such as travoprost and the surfactant is a vegetable oil such as castor oil.

Cette invention concerne l'élaboration de compositions pharmaceutiques. Les compositions comprennent un agent thérapeutique et une quantité relativement basse de tensioactif pour permettre une biodisponibilité plus élevée de l'agent thérapeutique. Les compositions sont particulièrement souhaitables à titre de compositions ophtalmiques, l'agent thérapeutique étant une prostaglandine telle que le travoprost et le tensioactif, une huile végétale telle que l'huile de ricin.

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