A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/385 (2006.01) A61K 39/08 (2006.01) A61K 39/095 (2006.01)
Patent
CA 2644724
Methods for preparing complex multivalent immunogenic conjugates that includ simultaneously reacting a plurality or immunogenic-distinct polysaccharides with at least one protein to make the complex multivalent immunogenic conjugates. The simultaneous reaction involves reaction of a hydrazide group on one reactant with an aldehyde or cyanat ester group on the other reactant.
L'invention a pour objet des procédés de préparation de conjugués immunogéniques multivalents complexes qui consistent notamment à faire réagir simultanément une pluralité de polysaccharides immunogéniques distincts avec au moins une protéine afin d'obtenir les conjugués immunogéniques multivalents complexes. La réaction simultanée implique la réaction d'un groupe hydrazide de l'un des réactifs à un groupe aldéhyde ou cyanate ester de l'autre réactif.
Smart & Biggar
The Government Of The United States Of America As Represented By
LandOfFree
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