A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/505 (2006.01) A61K 31/401 (2006.01) A61K 31/4184 (2006.01)
Patent
CA 2368186
The present invention relates to a new use of a statin drug in the improvement of diabetic neuropathy, specifically in improving nerve conduction velocity and nerve blood flow in patients suffering diabetes, in particular to pharmaceutical combinations of the statin drug and other agents known to improve diabetic neuropathy such as an aldose reductase inhibitor (ARI), an angiotensin converting enzyme (ACE) inhibitor or an angiotensin II (AII) antagonist which combinations are useful in the prevention and treatment of the complications of diabetes.
La présente invention concerne l'utilisation de statine dans l'amélioration de neuropathie diabétique, particulièrement par amélioration de la vitesse de conduction nerveuse et du débit sanguin nerveux chez des patients atteints de diabète. L'invention concerne, en particulier, des combinaisons pharmaceutiques de statine et d'autres agents, connus pour améliorer la neuropathie diabétique tels qu'un inhibiteur d'aldose réductase (ARI), un inhibiteur de l'enzyme de conversion de l'angiotensine (ACE) ou un antagoniste d'angiotensine II (AII), ces combinaisons étant utiles dans la prévention et le traitement de complications de diabètes.
Cameron Norman Eugene
Cotter Mary Anne
Astrazeneca Ab
Smart & Biggar
The University Court Of The University Of Aberdeen
LandOfFree
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