C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01) C12N 9/50 (2006.01)
Patent
CA 2580004
This invention describes compositions related to growth inhibitory protein- derived peptide fragments. These fragments can be identified by several methods including homology comparison and amino acid pairing techniques. Certain fragment sequences have been shown to provide homology to various biological activities and are contemplated as potential therapeutic agents. These biological activities include, but are not limited to, anti-cancer effects, nonselective calcium channel regulation, angiogenesis inhibition, cytoskeletal controls, cell cycle regulation, enzyme function, transcription, and anti-microbials.
L'invention concerne des compositions associées à des fragments peptidiques d'origine protéique inhibiteurs de croissance. Ces fragments peuvent être identifiés au moyen de diverses méthodes, telles que des techniques de comparaison par homologie et d'appariement d'acides aminés. On a observé que certaines séquences de fragments confèrent une homologie pour diverses activités biologiques, lesdites séquences étant considérées comme des agents thérapeutiques potentiels. Ces activités biologiques comprennent, entre autres, des effets anticancéreux, la régulation non sélective des canaux calciques, l'inhibition de l'angiogenèse, les régulations cytosquelettiques, la régulation du cycle cellulaire, la fonction enzymatique, la transcription et les effets antimicrobiens.
Serometrix Llc
Smart & Biggar
LandOfFree
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