A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/31 (2006.01) A61K 39/00 (2006.01) A61K 39/02 (2006.01) A61K 39/29 (2006.01) C07K 14/65 (2006.01) C07K 14/655 (2006.01)
Patent
CA 2329755
The invention provides peptides comprising somatostatin, or a sequence homologous to somatostatin, which is covalently linked to a helper T cell epitope and optionally to other immunostimulatory sequences. The present invention provides for the use of such peptides as immunogens to elicit the production in mammals of high titer polyclonal antibodies, which are specific to somatostatin. The peptides are expected to be useful in lowering somatostatin levels in mammals, thereby increasing growth rate and food utilization efficiency.
L'invention concerne des peptides comprenant de la somatostatine, ou une séquence homologue de la somatostatine, qui est liée par covalence à un épitope de lymphocytes T auxiliaires et éventuellement à leurs séquences immunostimulatrices. L'invention concerne également l'utilisation de ces peptides en tant qu'immunogènes pour déclencher, chez les animaux, la production d'anticorps polyclonaux à titre élevé qui sont spécifiques de la somatostatine. Ces peptides sont censés être utiles pour abaisser le taux de somatostatine chez les animaux, ce qui permet d'augmenter la vitesse de croissance et l'efficacité d'utilisation de la nourriture.
Mcfadden Fincham
United Biomedical Inc.
LandOfFree
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