A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/554 (2006.01) A61K 9/32 (2006.01) A61K 9/58 (2006.01) A61K 31/19 (2006.01) A61K 33/00 (2006.01) A61P 25/18 (2006.01)
Patent
CA 2595885
The invention relates to a formulation for the treatment of acute manic episodes associated with Bipolar I Disorder comprising an antipsychotic agent selected from the group consisting of: a dibenzothiazepine derivative; lithium; and divalproex. The formulation comprises a first component which comprises a first population the antipsychotic agent and at least one subsequent component which comprises a subsequent population of the antipsychotic agent and which allows for the modified release of the agent. The combination of the first and the subsequent components in operation deliver the antipsychotic agent in a pulsed or controlled manner over a period of up to twenty-four hours.
L'invention concerne une préparation destinée au traitement d'épisodes maniaques aigus associés au trouble bipolaire I et comprenant un agent antipsychotique choisi dans le groupe constitué par un dérivé de dibenzothiazépine, du lithium et du divalproex. Cette préparation comprend un premier constituant renfermant une première population de l'agent psychotique et au moins un second constituant renfermant une seconde population de l'agent antipsychotique et permettant une libération modifiée de l'agent. La combinaison desdits premier et second constituants lors d'une utilisation permet d'administrer l'agent antipsychotique de manière pulsée ou régulée sur une période pouvant atteindre 24 heures.
Jenkins Scott
Liversidge Gary
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Elan Pharma International Limited
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