Oral administration of a calcitonin

Details Oral administration of a calcitonin Oral administration of a calcitonin

A - Human Necessities

61

K

A61K 9/00 (2006.01)

Patent

CA 2679782

The invention is directed to a method of administering pharmaceutical compositions comprising peptide drugs such as a calcitonin in combination with one or more oral delivery agents, together with an amount of a liquid, and method of treatment of disorders responsive to the action of peptide drugs such as a calcitonin employing such method of administration so as to enhance the oral bioavailability of a calcitonin. The methods of the invention increase the oral absorption and systemic bioavailability of peptide drugs, such as a calcitonin.

La présente invention concerne un procédé d'administration de compositions pharmaceutiques comprenant des médicaments peptidiques tels qu'une calcitonine en association avec un ou des agents d'administration orale, conjointement à une quantité d'un liquide. L'invention concerne également un procédé de traitement de désordres sensibles à l'action de médicaments peptidiques tels qu'une calcitonine en utilisant un tel procédé d'administration de sorte à augmenter la biodisponibilité orale d'une calcitonine. Les procédés de l'invention augmentent l'absorption orale et la biodisponibilité systémique des médicaments peptidiques, tels qu'une calcitonine.

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