C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/439 (2006.01) A61K 31/496 (2006.01) A61K 31/551 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2623507
The present invention provides methods and compositions comprising compounds useful for stimulating neurogenesis. The methods and compositions comprising compounds are also useful for inhibiting neuronal degeneration. Thus, the present invention can be used in the treatment of diseases and conditions characterized by neuronal loss and reduced neurogenesis including Alzheimer's disease, stroke, traumatic brain injury, and depression. This invention could also be used for research products including single agents or mixtures of agents to promote, proliferate, differentiate, or maintain neurons from stem or progenitor cells.
L'invention concerne des méthodes et des compositions comprenant des composés utilisés pour stimuler la neurogénèse. On utilise ces méthodes et les compositions comprenant des composés pour inhiber la dégénérescence neuronale. En conséquence, cette invention peut être utilisée pour traiter des maladies et des états caractérisés par des pertes neuronales et une neurogénèse réduite, notamment, la maladie d'Alzheimer, les accidents vasculo-cérébraux, les lésions traumatiques du cerveau et la dépression. L'invention peut également être utilisée pour rechercher des produits, notamment, des agents uniques ou des mélanges d'agents afin de promouvoir, multiplier, différencier ou conserver les neurones provenant de cellules souches ou progénitrices.
Bennett Jones Llp
Neuronascent Inc.
LandOfFree
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