A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/48 (2006.01) A61K 9/58 (2006.01) A61K 31/4439 (2006.01) A61K 45/00 (2006.01) A61K 47/34 (2006.01) A61K 47/42 (2006.01) A61P 1/04 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2557634
A capsule in which an unstable active ingredient has been stabilized is obtained by lowering the moisture content of a solid preparation (granules, subtilis, tablets, etc.) containing a chemical unstable to moisture such as an imidazole PPI compound by drying or the like, and then filling in a capsule comprising a water-soluble polysaccharide such as pullulan as the main component or a PEG-containing gelatin capsule. For the further stabilization, the capsule per se may be dried. The capsule preparation thus obtained is a stable capsule preparation with the use of a capsule being stable at a low moisture content which contains a chemical unstable to moisture such as an imidazole compound.
Il est prévu une capsule dans laquelle on a stabilisé un ingrédient actif instable, capsule obtenue en abaissant la teneur en humidité d~une préparation solide (granulés, subtilis, comprimés, etc.) contenant un produit chimique instable à l~humidité comme par exemple un composé PPI imidazole, par séchage ou autre, puis en remplissant une capsule comprenant un polysaccharide soluble dans l~eau, comme du pullulane comme principal composant ou bien une capsule de gélatine contenant un PEG. Pour renforcer la stabilisation, on peut sécher la capsule proprement dite. La préparation de capsule ainsi obtenue est une préparation de capsule stable, à l~aide d~une capsule stable à une faible teneur en humidité, contenant un produit chimique instable à l~humidité comme par exemple un composé imidazole.
Ito Hiroki
Nagahara Naoki
Nonomura Muneo
Fetherstonhaugh & Co.
Takeda Pharmaceutical Company Limited
LandOfFree
Stable capsule preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Stable capsule preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stable capsule preparation will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1456715