C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 405/00 (2006.01) A61K 31/559 (2006.01) A61P 27/06 (2006.01) C07D 209/08 (2006.01) C07D 333/04 (2006.01)
Patent
CA 2628413
The present invention relates to cyclopentane heptenoic acid-5-cis-2-(3.alpha.- hydroxy or lower alkyloxy-5-thienylpentyl)-3, 5-dihydroxy, [1.alpha., 2.beta., 3.alpha., 5.alpha.] compounds, lower alkyl, hydroxyl lower alkyl and indole lower alkyl amides and esters thereof as potent ocular hypotensives that are particularly suited for the management of glaucoma.
La présente invention concerne des composés d'acide cyclopentane-hepténoïque-5-cis-2-(3a-hydroxy ou (alkyle inférieur)-oxy-5-thiénylpentyl)-3,5-dihydroxy, [1a, 2ß, 3a, 5a], des amides et esters d'alkyle inférieur, d'hydroxyalkyle inférieur et d'indole-(alkyle inférieur) de ceux-ci en tant qu'hypotenseur oculaire puissant qui sont particulièrement adaptés pour le traitement du glaucome.
Allergan Inc.
Gowling Lafleur Henderson Llp
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