Transdermal formulations of synthetic cannabinoids and nano...

A - Human Necessities – 61 – K

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Details

A61K 31/353 (2006.01) A61K 9/06 (2006.01) A61K 9/70 (2006.01) A61K 47/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2657332

The present invention relates to pharmaceutical compositions comprising cannabinoids or mimics thereof. In one aspect, the invention provides transdermal formulations comprising cannabinoids or mimics thereof. In another aspect, the invention provides topical formulations comprising cannabinoids or mimics thereof. In one embodiment the formulations and compositions of the invention comprise nano colloidal silica. The formulations of the invention can be used in the therapeutic treatment of many conditions, including wherein the cannabinoids or mimics thereof are known to reduce the excessive neuronal firing characteristic of neuropathic pain. Muscle spasticity is also benefited by these formulations.

La présente invention concerne des compositions pharmaceutiques contenant des cannabinoïdes ou des mimétiques de ces derniers. Selon un certain aspect, l'invention concerne des formulations transdermiques contenant des cannabinoïdes ou des mimétiques de ces derniers. Selon un autre aspect, l'invention concerne des formulations topiques contenant des cannabinoïdes ou des mimétiques de ces derniers. Selon un mode de réalisation, les formulations et compositions de l'invention contiennent de la silice nanocolloïdale. Les formulations de l'invention peuvent être utilisées dans le traitement thérapeutique de plusieurs pathologies, y compris celles face auxquelles les cannabinoïdes ou des mimétiques de ces derniers sont connus pour réduire la caractéristique de décharge neuronale excessive de la douleur neuropathique. La spasticité musculaire se traite également à l'aide desdites formulations.

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