Ophthalmic composition

A - Human Necessities – 61 – K

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A61K 31/58 (2006.01) A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61K 31/57 (2006.01) A61K 31/665 (2006.01) C07J 3/00 (2006.01) C07J 5/00 (2006.01) C07J 9/00 (2006.01) C07J 11/00 (2006.01) C07J 41/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 2064478

Pharmaceutical compositions useful in the treatment of ophthalmic inflammation and methods of treating ophthalmic in- flammation with those compositions ar disclosed. The compositions contain a combination of a glucocorticoid and an angiostatic steroid. The angiostatic steroid substantially prevents any significant increases in intraocular pressure which might otherwise he experienced by the patient as a side effect of the glucocorticoid component of the compositions. The therapeutic interaction of the two components therefore allows the potent anti-inflammatory properties of the glucocorticoids to be utilized without fear of ele- vating intraocular pressure.

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