A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4415 (2006.01) A61K 31/435 (2006.01) A61K 31/4355 (2006.01) A61K 31/44 (2006.01) A61K 31/5375 (2006.01) A61K 31/64 (2006.01) A61K 31/675 (2006.01) A61K 31/715 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2376029
Methods for treating diabetes mellitus and related conditions and symptoms are described. The methods are directed to administering a therapeutically effective amount of a compound. Compounds suitable for the invention include pyridoxal-5'-phosphate, pyridoxal, pyridoxamine, pyridoxine, a 3-acylated pyridoxal analogue, a pharmaceutically acceptable acid addition salt thereof, or a mixture thereof. Also disclosed are methods directed to concurrently administering a therapeutically effective amount of a compound with other compounds known in the treatment of diabetes mellitus. In one embodiment, a therapeutically effective amount of a compound is administered concurrently with a therapeutically effective amount of insulin. In another embodiment, a therapeutically effective amount of a compound is administered concurrently with a therapeutically effective amount of a hypoglycemic compound.
L'invention concerne des méthodes de traitement du diabète sucré et des conditions et symptômes qui lui sont associés. Les méthodes consistent à administrer une quantité pharmaceutiquement efficace d'un composé. Parmi les composés adéquats, figurent le pyridoxal-5'-phosphate, le pyridoxal, la pyridoxamine, la pyridoxine, un analogue 3-acylé de pyridoxal, un sel d'addition de ces derniers pharmaceutiquement acceptable, ou un mélange de ces derniers. L'invention concerne également des procédés consistant à administrer une quantité pharmaceutiquement efficace d'un composé simultanément à d'autres composés connus dans le traitement du diabète sucré. Dans un autre mode de réalisation, une quantité pharmaceutiquement efficace d'un composé est administrée simultanément à une quantité pharmaceutiquement efficace d'insuline. Dans un autre mode de réalisation encore, une quantité pharmaceutiquement efficace d'un composé est administrée simultanément à une quantité pharmaceutiquement efficace d'un composé hypoglycémique.
Haque Wasimul
Sethi Rajat
Medicure Inc.
Ridout & Maybee Llp
LandOfFree
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