Mutated xylose reductase in xylose-fermentation by s....

C - Chemistry – Metallurgy – 12 – N

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C12N 1/19 (2006.01)

Patent

CA 2561302

New xylose-utilizing Saccharomyces cerevisiae mutant strain which ferments xylose to ethanol, wherein the strain expresses a K270M mutated P. stipitis XYL1 gene (1 or 2 copies of the mutated gene) together with the native P. stipitis XYL2 gene and overexpresses the endogenous XKS1 gene.

La présente invention concerne une nouvelle souche mutante desaccharomyces cerevisiae utilisant le xylose fermentant le xylose en éthanol. Cette souche exprime un gène XYL1 de P. stipitis à mutation K270M (1 ou 2 copies du gène muté) conjointement avec le gène XYL2 de P. stipitis d'origine, et elle surexprime le gène XKS1 endogène.

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