Improved process for preparing 2-(substituted...

Details Improved process for preparing 2-(substituted... Improved process for preparing 2-(substituted...

C - Chemistry, Metallurgy

07

C

C07C 29/147 (2006.01) C07C 33/46 (2006.01) C07C 269/00 (2006.01) C07C 271/12 (2006.01)

Patent

CA 2702873

The present invention relates to a process of preparing a compound of Formula I: (I) Formula I Wherein R1 is defined in the specification. Compounds of Formula I are useful for treating disorders of the central nervous system, including epilepsy. The process includes a novel use of the reagent lithium borohydride.

La présente invention concerne un procédé de préparation d'un composé de formule I dans laquelle R1 est tel que défini dans le mémoire descriptif. Les composés de formule I se révèlent utiles dans le cadre du traitement de troubles du système nerveux central, dont l'épilepsie. Ce procédé comprend, en particulier, une utilisation inédite du réactif qu'est le borohydrure de lithium.

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