Method and apparatus for pulsed iontophoretic drug delivery

A - Human Necessities – 61 – N

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A61N 1/30 (2006.01) A61N 1/32 (2006.01)

Patent

CA 2069750

A method and apparatus are disclosed for transdermal inotophoretic delivery of ionic species, such as a drug in ionic form, in which electrical pulses having controlled, distinctive, dual-segment waveform characteristics are applied. The therapeutic pulses are generated at a predetermined frequency and have a predetermined pulse width. First (20) and second (22) pulse segment generator means generate pulse segments which are applied to the patient skin through active (16) and indifferent (18) electrodes. The electrical attributes of each pulse segment, including amplitude and duration, are controlled to produce the desired, pulsed output waveform.

Procédé et appareil d'administration iontophorétique transdermique d'espèces ioniques, telles qu'un médicament sous forme ionique, selon lesquels des impulsions électriques ayant des caractéristiques de formes d'ondes régulées, distinctes et à double segment sont appliquées. Les impulsions thérapeutiques sont générées à une fréquence prédéterminée et ont une largeur d'impulsion prédéterminée. Des premiers (20) et des seconds (22) moyens générateurs de segments d'impulsions génèrent des segments d'impulsions qui sont appliqués sur la peau du patient par l'intermédiaire d'une électrode active (16) et d'une électrode indifférente (18).

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