C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/22 (2006.01) A61K 31/445 (2006.01)
Patent
CA 2609440
The invention provides a class of dopamine transporter inhibitors of formula (I) (DAT inhibitors) , packaged pharmaceuticals comprising such inhibitors, and their uses in treating, or the manufacturing medicaments for treating disease conditions, inlcuding Parkinson's disease, Hoehn and Yahr Staging of Parkinson's Disease, Unified Parkinson Disease Rating Scale (UPDRS), and Schwab and England Activities of Daily Living Scale. Related business methods such as marketing the inhibitors to healthcare providers are also provided.
L'invention porte sur une classe d'inhibiteurs des transporteurs de la dopamine de la formule (I), sur des préparations pharmaceutiques les contenant et sur leur utilisation pour traiter différentes maladies dont la maladie de Parkinson; en utilisant la stadification de Hoehn et Yahr de la maladie de Parkinson, l'échelle d'évaluation unifiée de la maladie de Parkinson (UPDRS), et l'échelle de Schwab et England relative aux activités de la vie quotidienne. L'invention porte également sur les procédés d'obtention et les méthodes commerciales associées de vente à des prestataires de soins, de ces inhibiteurs.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Prexa Pharmaceuticals Inc.
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