Production of gm-csf in plants

Details Production of gm-csf in plants Production of gm-csf in plants

C - Chemistry, Metallurgy

12

N

C12N 15/27 (2006.01) A01H 5/00 (2006.01) A01H 5/10 (2006.01) C12N 5/04 (2006.01) C12N 5/10 (2006.01) C12N 15/82 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2451001

The present invention discloses a method of producing granulocyte-macrophage colony stimulating factor (GM-CSF) in a plant comprising, transforming the plant with a genetic construct comprising a regulatory region functional in the plant, operably associated with a GM-CSF coding sequence, or a fragment or a derivative thereof, operably associated with a transcriptional terminator, and expressing the GM- CSF. Also disclosed are transgenic plants, seeds and cells comprising GM-CSF coding sequences and plant optimized GM-CSF coding sequences.

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