Induction of anti-tumor cytotoxic t lymphocytes in humans...

Details Induction of anti-tumor cytotoxic t lymphocytes in humans... Induction of anti-tumor cytotoxic t lymphocytes in humans...

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 35/14 (2006.01) C07K 14/33 (2006.01) C07K 14/47 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2181920

The present invention relates to compositions and methods for treating cancer. The invention provides peptides based on a 9-residue epitope derived from the product of the tumor-associated gene MAGE-3. The peptide induces CTL that kill melanoma and other tumor cells lines.

Cette invention se rapporte à des compositions et à des procédés de traitement du cancer. Elle décrit des peptides à base d'un épitope à 9 résidus dérivé du produit du gène associé aux tumeurs MAGE-3. Ce peptide induit des lymphocytes T cytotoxiques qui tuent les mélanomes ainsi que les autres lignées de cellules tumorales.

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