Indole derivatives as serotonin reuptake inhibitors

Details Indole derivatives as serotonin reuptake inhibitors Indole derivatives as serotonin reuptake inhibitors

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/4045 (2006.01) A61P 25/00 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2529298

The invention relates to compounds of formula (I) used for producing drugs for treating diseases related to a serotonin receptor and/or a serotonin reabsorption, in particular for producing drugs like anxiolitic, antidepressive, neuroleptic and/or antihypertensive drugs and/or for positively influencing obsessional compulsive troubles, sleep disorders, tardive dyskinesia, learning troubles, gerontal memory loss, eating disorders such as bulimia and/or irritable bowel syndrome and/or sexual function troubles. Said compounds are associated with to a 5-HT1A receptor.

Composés de formule (I), utilisation desdits composés pour produire un médicament destiné à traiter des maladies liées au récepteur de la sérotonine et / ou à la réabsorption de la sérotonine, en particulier pour produire un médicament de type anxiolytique, antidépresseur, neuroleptique et / ou antihypertonique et / ou pour influencer positivement les troubles obsessionnels-compulsifs, les troubles du sommeil, la dyskinésie tardive, les troubles de l'apprentissage, les troubles de la mémoire liés à l'âge, les troubles alimentaires tels que la boulimie et / ou le syndrome du colon irritable et / ou les troubles de la fonction sexuelle. Lesdits composés se lient au récepteur 5-HT1A.

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