High specificity marker detection

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 31/7034 (2006.01) A61K 31/7048 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2404428

This invention provides methods of detecting the presence of a disseminated cell marker in a sample by eliminating illegitimate transcription-positive cells from the sample and detecting the presence of mRNA that encodes the marker. This invention also provides methods of detecting disseminated cancer cells.

Cette invention a trait à des techniques permettant de détecter la présence d'un marqueur cellulaire disséminé dans un prélèvement, par élimination dans le prélèvement de cellules positives à transcription asymétrique ainsi que par détection de la présence d'ARN messager codant le marqueur. Cette invention porte également sur des procédés de détection de cellules cancéreuses disséminées.

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