Quinazoline derivatives for the treatment of tumours

Details Quinazoline derivatives for the treatment of tumours Quinazoline derivatives for the treatment of tumours

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2407371

The invention concerns quinazoline derivatives of Formula (I) wherein each of Q1, Z, m, R1, R2, R3 and Q2 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medica-ment for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.

L'invention concerne des dérivés de la quinazoline de la formule I, dans laquelle la signification de chacun des Q<1>, Z, m, R<1>, R<3> et Q<2> est telle que définie dans le descriptif. Elle concerne en outre leurs procédés de préparation, les compositions pharmaceutiques les contenant et leur utilisation dans la fabrication d'un médicament servant d'agent anti-invasif permettant d'endiguer et/ou de traiter une tumeur solide.

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