Use of flagellin in tumor immunotherapy

Details Use of flagellin in tumor immunotherapy Use of flagellin in tumor immunotherapy

A - Human Necessities

61

K

A61K 39/02 (2006.01)

Patent

CA 2589556

The invention provides a fusion protein comprising a flagellin adjuvant and a tumor antigen. Also provided are compositions comprising a flagellin adjuvant and a tumor antigen. The invention further provides pharmaceutical formulations and methods for inducing an immune response against a tumor antigen and methods of treating a tumor in a subject.

La présente invention concerne une protéine de fusion comprenant un adjuvant de flagelline et un antigène tumoral, des compositions comprenant un adjuvant de flagelline et un antigène tumoral, des procédés pour produire une protéine de fusion comprenant un adjuvant de flagelline et un antigène tumoral, des préparations pharmaceutiques et des procédés pour induire une réponse immunitaire à l'encontre d'un antigène tumoral, ainsi que des procédés pour traiter une tumeur chez un sujet.

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