Controlled-release pharmaceutical composition with gastric...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 9/46 (2006.01) A61K 31/166 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2347105

The invention concerns a pharmaceutical composition with gastric residence and controlled release, characterised in that it comprises two or three layers and contains: (a) an active principle associated with a excipient modifying its release; (b) a system generating carbon dioxide in a swelling polymer hydrophilic matrix; (a) and (b) capable of being included in a common layer or in separate layers

Composition pharmaceutique à résidence gastrique et à libération contrôlée, caractérisée en ce qu'elle comporte deux ou trois couches et en ce qu'elle comprend: (a) un principe actif associé à un excipient modifiant sa libération, (b) un système générateur de dioxyde de carbone dans une matrice hydrophile polymérique gonflante, (a) et (b) pouvant être compris dans une même couche ou dans des couches distinctes.

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