C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2463920
Methods for diagnosing and monitoring ovarian carcinoma in a subject are described comprising measuring KLK9 or hK9 in a sample from the subject. The invention also provides localization or imaging methods for ovarian cancer, and kits for carrying out the methods of the invention. The invention also contemplates therapeutic applications for ovarian cancer employing hK9 proteins, nucleic acid molecules encoding the proteins, and/or binding agents for the proteins.
L'invention concerne des méthodes de diagnostic et de contrôle de carcinomes de l'ovaire chez un sujet consistant à mesurer KLK9 ou hK9 dans un échantillon prélevé sur un sujet. L'invention concerne également des méthodes de localisation ou d'imagerie pour le cancer de l'ovaire ainsi que des matériels de mise en application des méthodes de l'invention. L'invention a également trait à des applications thérapeutiques pour le cancer de l'ovaire utilisant des protéines hK9, des molécules d'acide nucléique codant les protéines et/ou des agents de fixation pour les protéines.
Diamandis Eleftherios
Yousef George M.
Mccarthy Tetrault Llp
Mount Sinai Hospital
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