Preparation of levalbuterol hydrochloride

Details Preparation of levalbuterol hydrochloride Preparation of levalbuterol hydrochloride

C - Chemistry, Metallurgy

07

C

C07C 213/10 (2006.01) A61K 31/135 (2006.01) A61P 11/00 (2006.01) C07C 215/60 (2006.01) C07C 217/48 (2006.01)

Patent

CA 2556904

Provided are processes for the preparation of (R)-SLB.D-DBTA salt and levalbuterol hydrochloride. Also provided are levalbuterol hydrochloride degradation products and processes for preparing them. Pharmaceutical compositions comprising at least one levalbuterol hydrochloride of the invention and at least one pharmaceutically-acceptable excipient are also provided.

Sont dévoilés des procédés pour préparer du sel (R)-SLB.D-DBTA et du chlorhydrate de levalbuterol. Sont également dévoilés des produits pour dégrader le chlorhydrate de levalbuterol et des procédés pour les préparer. Sont également dévoilés des préparations pharmaceutiques comprenant au moins un des chlorhydrates de levalbuterol de l~invention et au moins un excipient acceptable d~un point de vue pharmaceutique.

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