Process for the preparation of 2-substituted...

Details Process for the preparation of 2-substituted... Process for the preparation of 2-substituted...

C - Chemistry, Metallurgy

07

D

C07D 233/68 (2006.01)

Patent

CA 2194119

A novel process for the preparation of 2-substituted 5- chloroimidazole-4-carbaldehydes of the general formula: (see formula I) wherein R denotes hydrogen, alkyl, alkenyl, cycloalkyl, arylalkyl or aryl, in which glycine is reacted with an imido ester of the general formula: (see formula II) wherein R is as above and R1 is alkyl, and the resulting intermediate is converted into the target product by a Vilsmeier reagent. The 2-substituted 5-chloroimidazole-4- carbaldehydes (I) are valuable intermediates in the preparation of pharmaceuticals or of herbicidally active compounds.

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