Cytokine-expressing cellular vaccine combinations

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61K 31/337 (2006.01) A61K 31/415 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 38/21 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2519563

The present invention in all of its associated aspects provides improved methods and compositions for treating cancer in a mammal based on the administration of the combination of a cytokine-expressing cellular vaccine and at least one additional cancer therapeutic agent or treatment to a patient with cancer, wherein administration of the combination results in enhanced therapeutic efficacy relative to administration of the cytokine-expressing cellular vaccine or cancer therapeutic agent or treatment as a monotherapy.

La présente invention porte sur des procédés améliorés et sur des compositions visant à traiter le cancer chez un mammifère sur la base de l'administration à un patient atteint d'un cancer de la combinaison d'un vaccin cellulaire exprimant la cytokine et d'au moins d'un agent ou traitement anticancéreux additionnel. L'administration de cette combinaison entraîne une meilleure efficacité thérapeutique par rapport à l'administration du vaccin cellulaire exprimant la cytokine ou d'un agent ou traitement anticancéreux tel qu'une monothérapie.

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