Medicine consisting of concomitant use or combination of...

A - Human Necessities – 61 – K

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A61K 31/519 (2006.01) A61K 31/155 (2006.01) A61K 31/455 (2006.01) A61K 45/00 (2006.01) A61P 3/10 (2006.01) A61P 43/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2724133

The problem to be solved by the present invention is to provide a medicine which is excellent in the treatment of type 2 diabetes, diabetic complications or impaired glucose tolerance. The present invention provides a medicine characterized in that a compound represented by the following general formula (I) , a salt thereof, or a solvate thereof, and at least one kind of other diabetic medicine: (see formula I) (wherein R1, R2, R3 and R4 are each a hydrogen atom, a trifluoromethyl group or a C1-3 alkyl group).

L'invention porte sur une préparation pharmaceutique qui est très utile pour le traitement du diabète de type 2, de complications diabétiques ou d'une tolérance au glucose défectueuse. La préparation pharmaceutique est caractérisée par le fait qu'un composé représenté par la formule générale (I), qu'un sel du composé ou qu'un solvate du composé ou du sel et qu'au moins un autre agent thérapeutique du diabète sont administrés en combinaison. [Dans la formule générale (I), R1, R2, R3 et R4 représentent indépendamment un atome d'hydrogène, un groupe trifluorométhyle ou un groupe alkyle C1-3].

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