Triptolide prodrugs having high aqueous solubility

Details Triptolide prodrugs having high aqueous solubility Triptolide prodrugs having high aqueous solubility

C - Chemistry, Metallurgy

07

D

C07D 493/22 (2006.01) C07D 233/02 (2006.01) C07D 303/17 (2006.01) C07D 303/31 (2006.01) C07D 307/77 (2006.01) C07D 405/14 (2006.01) C07D 407/14 (2006.01) C07D 493/14 (2006.01)

Patent

CA 2342901

Compounds useful in immunosuppressive and anti-inflammatory treatment are described. The compounds are hydrolyzable triptolide analogs with improved water solubility and generally lower toxicity than the parent compound.

L'invention concerne des composés utiles dans les traitements anti-inflammatoires et immunosuppresseurs. Ces composés sont des analogues de triptolides présentant une meilleure solubilité dans l'eau, et une toxicité généralement faible par rapport au composé parent.

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