Live attenuated salmonella vaccine

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 1/20 (2006.01) A61K 39/108 (2006.01) A61K 39/112 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2646421

The present invention relates to attenuated guaB deletion mutants of a bacterium infecting veterinary species, more in particular Salmonella enterica, to their use and production. The present invention further relates to live attenuated vaccines based on such mutants for preventing bacterial infections, and more in particular Salmonellosis, in a veterinary species, more in particular poultry.

L'invention porte sur des mutants à délétion guaB atténués d'une bactérie infectant les espèces vétérinaires, en particulier Salmonella enterica, sur leur utilisation et sur leur production. L'invention concerne également des vaccins vivants atténués fondés sur lesdits mutants, qui sont destinés à prévenir les infections bactériennes, en particulier la salmonellose, chez une espèce vétérinaire, en particulier la volaille.

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