Stable oral formulation containing benzimidazole derivative

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/4439 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 31/355 (2006.01) A61K 31/44 (2006.01)

Patent

CA 2426175

An enteric formulation containing at least one benzimidazole derivative, said formulation comprising: a core containing at least one benzimidazole derivative and at least one lipophilic antioxidant, and an enteric envelope protecting the core at least at a pH of 3 to 5, preferably at a pH pf 1 to 5.

L'invention concerne une formulation entérique renfermant au moins un dérivé de benzimidazole, composée de la manière suivante: un noyau qui contient au moins un dérivé de benzimidazole et au moins un antioxydant lipophile, et une enveloppe entérique de protection du noyau ayant un pH au moins compris entre 3 et 5, et de préférence compris entre 1 et 5.

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