Stromal cell-derived factor-1 mediates stem cell homing and...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01)

Patent

CA 2504019

method of treating infarcted myocardial tissue includes, the concentration of SDF-1 protein in the infarcted tissue. The concentration of stem cells in the peripheral blood of the infarcted tissue is also increased. The number of stem cells in the peripheral blood is increased while the concentration of SDF-1 in the infarcted tissue is increased.

L'invention concerne une méthode qui permet de traiter les tissus myocardiques infarcis et qui consiste à augmenter la concentration de protéines SDF-1 dans un tissu infarci. La concentration de cellules souches dans le sang périphérique du tissu infarci est également augmentée. Le nombre de cellules souches comprises dans le sang périphérique est augmenté tout comme la concentration de SDF-1 dans le tissu infarci.

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