C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 477/14 (2006.01) A61K 31/40 (2006.01)
Patent
CA 2298997
The present invention relates to carbapenem antibacterial agents in which the carbapenem nucleus is substituted at the 2-position with a naphthosultam linked through a CH2 group. The napththosultam is further substituted with various substituent groups including at least one cationic group.
Cette invention se rapporte à des agents antibactériens à base de carbapenems, dans lesquels le noyau de carbapenem est substitué dans la position 2 par un naphtosultame lié par un groupe CH¿2?. Le naphtosultame est ensuite substitué par divers groupes substituants, y compris un groupe cationique au moins.
Blizzard Timothy A.
Morgan Jerry D.
Ratcliffe Ronald W.
Wilkening Robert R.
Merck & Co. Inc.
Ogilvy Renault
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