Hiv p17 assays for monitoring development of aids

G - Physics – 01 – N

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G01N 33/536 (2006.01) G01N 33/569 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2045686

2045686 9008959 PCTABS00001 Disease state of individuals who are seropositive for antibodies to HIV can be monitored and predicted by intermittently determining the level of HIV p17 and/or free complexing anti-p17 antibody in a body fluid. Levels of HIV p24 and free complexing anti-p24 can be simultaneously determined for information of maximum prognostic significance. Level of p17 can be measured by means of a heterogeneous sandwich ELISA. Level of anti-p17 antibody can be measured by means of a binding capacity assay using the same ELISA and exogenous p17.

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